Active Comparator: Arm I: Patients receive cisplatin IV over 60-90 minutes on days 1, 8, 15, 22, and 29. Patients also undergo external-beam radiation therapy once daily, 5 days a week, for approximately 5 weeks. Patients then undergo high-dose rate, pulsed-dose rate, or low-dose rate intracavitary brachytherapy.
Experimental: Arm I: Patients receive paclitaxel IV over 3 hours and carboplatin IV over 30-60 minutes on day 1.
http://www.Clinitical Trials.gov (NCT01045226)
The primary objective of this study is to see whether tinnitus retraining therapy or the standard of care is better for treating severe tinnitus.
Participants will be asked to complete questionnaires and assessments, take hearing tests, and visit a study audiologist 7 times over an 18 month period.
Participants can be excluded from the study if tinnitus does not interefere with daily activities, hearing acuity does not meet pre-determined criteria, tinnitus symptoms can be treated medically, or if participant currently uses hearing aids or has been treated for tinnitus within the last year.